A Nozaki-Hiyama-Kishi Ni(II)/Cr(II) coupling approach to the phomactins.
نویسندگان
چکیده
[reaction: see text] Through a unified synthetic strategy, appropriately functionalized bicyclic starting materials can be elaborated via Ni(II)/Cr(II) macrocylization to [9.3.1] bicycles. Elaboration of these core structures allows access to phomactin C/D analogues and establishes the first synthetic approach to phomactin A affording an intact octahydrochromene/macrocyclic ring system.
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ورودعنوان ژورنال:
- Organic letters
دوره 3 10 شماره
صفحات -
تاریخ انتشار 2001